Home › Top 5 Car Rental in Port St. Lucie, Florida Find best Car Rental in Port St. Lucie, Florida, with all necessary contact information, including addresses, phone numbers, working hours, map locations, and website links. Enterprise Rent-A-Car - Port St. Lucie (FL 34952) US, Port St. Lucie, FL 3495210502 S U.S. Hwy 1 Avis Car Rental - Port St. Lucie (FL 34952) US, Port St. Lucie, FL 349528617 S U.S. Hwy 1 Suite 9 Enterprise Rent-A-Car - Port St. Lucie (FL 34983) US, Port St. Lucie, FL 349831290 SW Bayshore Blvd Hertz Car Rental - Port Saint Lucie - Port Saint Lucie West HLE US, Port St. Lucie, FL 349862080 NW Courtyard Cir Budget Car Rental - Port St. Lucie US, Port St. Lucie, FL 349528617 S US Hwy 1 Ste 9